Q49* (p.Gln49Ter) variant of ICOS (Inducible T-cell costimulator)
Q49* (p.Gln49Ter) in ICOS (Inducible T-cell costimulator) is a protein-truncating change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.51 / 1. The record also includes population frequency data, published literature, and structural context.
Q49* (p.Gln49Ter) variant details
- p.Gln49Ter
- gnomAD 2-203955722-C-T
- Stop Gained
- Variant Prioritization Score for Impact Estimate 0.506
- CADD 34.00
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available
- Literature evidence available