N89D (p.Asn89Asp) variant of ICOS (Inducible T-cell costimulator)
N89D (p.Asn89Asp) in ICOS (Inducible T-cell costimulator) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.21 / 1. The record also includes population frequency data and structural context.
N89D (p.Asn89Asp) variant details
- p.Asn89Asp
- gnomAD rs1690068323
- Missense
- Variant Prioritization Score for Impact Estimate 0.21
- REVEL 0.07
- MetaLR 0.09
- MetaSVM -0.92
- CADD 16.10
- SIFT 0.05
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available