N73S (p.Asn73Ser) variant of ICOS (Inducible T-cell costimulator)
N73S (p.Asn73Ser) in ICOS (Inducible T-cell costimulator) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.28 / 1. The record also includes population frequency data, published literature, and structural context.
N73S (p.Asn73Ser) variant details
- p.Asn73Ser
- gnomAD 2-203955795-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.279
- REVEL 0.03
- MetaLR 0.07
- MetaSVM -1.01
- CADD 8.81
- PolyPhen-2 0.02
- SIFT 0.11
- Population evidence available
- Structural context available
- Literature evidence available