N23S (p.Asn23Ser) variant of ICOS (Inducible T-cell costimulator)
N23S (p.Asn23Ser) in ICOS (Inducible T-cell costimulator) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.16 / 1. The record also includes population frequency data and structural context.
N23S (p.Asn23Ser) variant details
- p.Asn23Ser
- Ensembl rs1690064207
- Missense
- Variant Prioritization Score for Impact Estimate 0.162
- REVEL 0.06
- MetaLR 0.13
- MetaSVM -0.97
- CADD 17.70
- PolyPhen-2 0.03
- SIFT 0.04
- Most common in the South Asian population (allele frequency 0.00021)
- Structural context available