M30V (p.Met30Val) variant of ICOS (Inducible T-cell costimulator)
M30V (p.Met30Val) in ICOS (Inducible T-cell costimulator) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data and structural context.
M30V (p.Met30Val) variant details
- p.Met30Val
- gnomAD rs1690064814
- Missense
- Variant Prioritization Score for Impact Estimate 0.271
- REVEL 0.13
- MetaLR 0.09
- MetaSVM -1.05
- CADD 21.70
- PolyPhen-2 0.08
- SIFT 0.06
- Most common in the Finnish in Finland (FIN) population (allele frequency 9.4e-05)
- Structural context available