K78R (p.Lys78Arg) variant of ICOS (Inducible T-cell costimulator)
K78R (p.Lys78Arg) in ICOS (Inducible T-cell costimulator) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.08 / 1. The record also includes population frequency data, published literature, and structural context.
K78R (p.Lys78Arg) variant details
- p.Lys78Arg
- gnomAD 2-203955810-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.0776
- REVEL 0.02
- MetaLR 0.04
- MetaSVM -1.02
- CADD 4.17
- PolyPhen-2 0.00
- SIFT 0.12
- Population evidence available
- Structural context available
- Literature evidence available