K67R (p.Lys67Arg) variant of ICOS (Inducible T-cell costimulator)
K67R (p.Lys67Arg) in ICOS (Inducible T-cell costimulator) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.14 / 1. The record also includes population frequency data, published literature, and structural context.
K67R (p.Lys67Arg) variant details
- p.Lys67Arg
- gnomAD 2-203955777-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.137
- REVEL 0.02
- MetaLR 0.04
- MetaSVM -1.00
- CADD 14.70
- PolyPhen-2 0.01
- SIFT 0.21
- Population evidence available
- Structural context available
- Literature evidence available