I32V (p.Ile32Val) variant of ICOS (Inducible T-cell costimulator)
I32V (p.Ile32Val) in ICOS (Inducible T-cell costimulator) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.09 / 1. The record also includes population frequency data and structural context.
I32V (p.Ile32Val) variant details
- p.Ile32Val
- ExAC rs750601214
- TOPMed rs750601214
- gnomAD rs750601214
- Missense
- Variant Prioritization Score for Impact Estimate 0.0867
- REVEL 0.02
- MetaLR 0.04
- MetaSVM -1.04
- CADD 7.66
- PolyPhen-2 0.00
- SIFT 0.74
- Most common in the Latino/Admixed American population (allele frequency 8.9e-05)
- Structural context available