I32M (p.Ile32Met) variant of ICOS (Inducible T-cell costimulator)
I32M (p.Ile32Met) in ICOS (Inducible T-cell costimulator) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.06 / 1. The record also includes population frequency data and structural context.
I32M (p.Ile32Met) variant details
- p.Ile32Met
- ExAC rs756151476
- TOPMed rs756151476
- gnomAD rs756151476
- Missense
- Variant Prioritization Score for Impact Estimate 0.0639
- REVEL 0.01
- MetaLR 0.08
- MetaSVM -1.02
- CADD 0.66
- PolyPhen-2 0.00
- SIFT 0.12
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available