G4V (p.Gly4Val) variant of ICOS (Inducible T-cell costimulator)
G4V (p.Gly4Val) in ICOS (Inducible T-cell costimulator) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.09 / 1. The record also includes population frequency data, published literature, and structural context.
G4V (p.Gly4Val) variant details
- p.Gly4Val
- gnomAD 2-203936825-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.0873
- REVEL 0.01
- MetaLR 0.03
- MetaSVM -1.06
- CADD 6.11
- PolyPhen-2 0.00
- SIFT 0.76
- Population evidence available
- Structural context available
- Literature evidence available