G20R (p.Gly20Arg) variant of ICOS (Inducible T-cell costimulator)
G20R (p.Gly20Arg) in ICOS (Inducible T-cell costimulator) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data, published literature, and structural context.
G20R (p.Gly20Arg) variant details
- p.Gly20Arg
- gnomAD 2-203936872-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.336
- REVEL 0.14
- MetaLR 0.19
- MetaSVM -0.55
- CADD 24.40
- PolyPhen-2 0.07
- SIFT 0.05
- Population evidence available
- Structural context available
- Literature evidence available