V15L (p.Val15Leu) variant of IAPP (Islet amyloid polypeptide)
V15L (p.Val15Leu) in IAPP (Islet amyloid polypeptide) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.10 / 1. The record also includes population frequency data, published literature, and structural context.
V15L (p.Val15Leu) variant details
- p.Val15Leu
- gnomAD 12-21373394-G-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.0965
- REVEL 0.12
- CADD 1.47
- PolyPhen-2 0.02
- SIFT 0.18
- Population evidence available
- Structural context available
- Literature evidence available