V15A (p.Val15Ala) variant of IAPP (Islet amyloid polypeptide)
V15A (p.Val15Ala) in IAPP (Islet amyloid polypeptide) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.20 / 1. The record also includes population frequency data and structural context.
V15A (p.Val15Ala) variant details
- p.Val15Ala
- ExAC rs778403247
- TOPMed rs778403247
- gnomAD rs778403247
- Missense
- Variant Prioritization Score for Impact Estimate 0.198
- REVEL 0.15
- CADD 13.40
- PolyPhen-2 0.03
- SIFT 0.11
- Most common in the REMAINING population (allele frequency 3.3e-05)
- Structural context available