S27S (p.Ser27Ser) variant of IAPP (Islet amyloid polypeptide)
S27S (p.Ser27Ser) in IAPP (Islet amyloid polypeptide) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.19 / 1. The record also includes population frequency data, published literature, and structural context.
S27S (p.Ser27Ser) variant details
- p.Ser27Ser
- rs182577227
- gnomAD 12-21373669-A-G
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.187
- CADD 15.00
- Most common in the 1KG:ASW population (allele frequency 0.0098)
- Structural context available
- Literature evidence available