S27N (p.Ser27Asn) variant of IAPP (Islet amyloid polypeptide)
S27N (p.Ser27Asn) in IAPP (Islet amyloid polypeptide) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes structural context.
S27N (p.Ser27Asn) variant details
- p.Ser27Asn
- rs1286099292
- NCI-TCGA Cosmic COSV5371
- cosmic curated COSV53714
- Ensembl rs1286099292
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.339
- AlphaMissense 0.13
- MetaLR 0.06
- MetaSVM -1.04
- MutPred 0.30
- UniProt: Variant assessed as somatic; moderate impact.
- Structural context available