R44G (p.Arg44Gly) variant of IAPP (Islet amyloid polypeptide)
R44G (p.Arg44Gly) in IAPP (Islet amyloid polypeptide) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.30 / 1. The record also includes population frequency data and structural context.
R44G (p.Arg44Gly) variant details
- p.Arg44Gly
- ExAC rs763676184
- TOPMed rs763676184
- gnomAD rs763676184
- Missense
- Variant Prioritization Score for Impact Estimate 0.298
- REVEL 0.28
- CADD 24.20
- Most common in the Latino/Admixed American population (allele frequency 6.5e-05)
- Structural context available