R33S (p.Arg33Ser) variant of IAPP (Islet amyloid polypeptide)
R33S (p.Arg33Ser) in IAPP (Islet amyloid polypeptide) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.44 / 1. The record also includes population frequency data, published literature, and structural context.
R33S (p.Arg33Ser) variant details
- p.Arg33Ser
- rs976582409
- gnomAD 12-21373672-A-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.443
- CADD 18.80
- Most common in the Latino/Admixed American population (allele frequency 6.5e-05)
- Structural context available
- Literature evidence available