R33K (p.Arg33Lys) variant of IAPP (Islet amyloid polypeptide)
R33K (p.Arg33Lys) in IAPP (Islet amyloid polypeptide) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.30 / 1. The record also includes population frequency data, published literature, and structural context.
R33K (p.Arg33Lys) variant details
- p.Arg33Lys
- rs1377330495
- gnomAD 12-21373671-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.299
- CADD 16.80
- Most common in the African/African-American population (allele frequency 6.4e-05)
- Structural context available
- Literature evidence available