Q7R (p.Gln7Arg) variant of IAPP (Islet amyloid polypeptide)
Q7R (p.Gln7Arg) in IAPP (Islet amyloid polypeptide) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.21 / 1. The record also includes population frequency data and structural context.
Q7R (p.Gln7Arg) variant details
- p.Gln7Arg
- 1000Genomes rs200933325
- ESP rs200933325
- ExAC rs200933325
- TOPMed rs200933325
- Missense
- Variant Prioritization Score for Impact Estimate 0.208
- REVEL 0.15
- CADD 13.80
- PolyPhen-2 0.00
- SIFT 0.01
- Most common in the 1KG:YRI population (allele frequency 0.0043)
- Structural context available