Q29K (p.Gln29Lys) variant of IAPP (Islet amyloid polypeptide)
Q29K (p.Gln29Lys) in IAPP (Islet amyloid polypeptide) is a protein-truncating change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.11 / 1. The record also includes population frequency data, published literature, and structural context.
Q29K (p.Gln29Lys) variant details
- p.Gln29Lys
- gnomAD 12-21376351-GT-G
- Frameshift
- Variant Prioritization Score for Impact Estimate 0.11
- CADD 4.20
- Most common in the Non-Finnish European population (allele frequency 9.4e-06)
- Structural context available
- Literature evidence available