N36Y (p.Asn36Tyr) variant of IAPP (Islet amyloid polypeptide)
N36Y (p.Asn36Tyr) in IAPP (Islet amyloid polypeptide) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.22 / 1. The record also includes population frequency data and structural context.
N36Y (p.Asn36Tyr) variant details
- p.Asn36Tyr
- ESP rs142526620
- ExAC rs142526620
- TOPMed rs142526620
- gnomAD rs142526620
- Missense
- Variant Prioritization Score for Impact Estimate 0.222
- REVEL 0.19
- CADD 20.60
- PolyPhen-2 0.12
- SIFT 0.00
- Most common in the African/African-American population (allele frequency 4.8e-05)
- Structural context available