N36S (p.Asn36Ser) variant of IAPP (Islet amyloid polypeptide)
N36S (p.Asn36Ser) in IAPP (Islet amyloid polypeptide) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.23 / 1. The record also includes population frequency data and structural context.
N36S (p.Asn36Ser) variant details
- p.Asn36Ser
- Ensembl rs2137113837
- Missense
- Variant Prioritization Score for Impact Estimate 0.232
- REVEL 0.10
- CADD 21.50
- PolyPhen-2 0.13
- SIFT 0.05
- Most common in the Non-Finnish European population (allele frequency 3.6e-06)
- Structural context available