N18Y (p.Asn18Tyr) variant of IAPP (Islet amyloid polypeptide)
N18Y (p.Asn18Tyr) in IAPP (Islet amyloid polypeptide) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.16 / 1. The record also includes population frequency data, published literature, and structural context.
N18Y (p.Asn18Tyr) variant details
- p.Asn18Tyr
- gnomAD 12-21373403-A-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.156
- REVEL 0.10
- CADD 15.40
- PolyPhen-2 0.01
- SIFT 0.01
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available
- Literature evidence available