L45F (p.Leu45Phe) variant of IAPP (Islet amyloid polypeptide)
L45F (p.Leu45Phe) in IAPP (Islet amyloid polypeptide) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.09 / 1. The record also includes population frequency data, published literature, and structural context.
L45F (p.Leu45Phe) variant details
- p.Leu45Phe
- gnomAD 12-21373666-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.0877
- CADD 1.00
- Most common in the REMAINING population (allele frequency 3.3e-05)
- Structural context available
- Literature evidence available