L17L (p.Leu17Leu) variant of IAPP (Islet amyloid polypeptide)
L17L (p.Leu17Leu) in IAPP (Islet amyloid polypeptide) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.09 / 1. The record also includes population frequency data, published literature, and structural context.
L17L (p.Leu17Leu) variant details
- p.Leu17Leu
- rs548820504
- gnomAD 12-21373400-T-C
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.0868
- CADD 0.87
- Most common in the 1KG:ESN population (allele frequency 0.0049)
- Structural context available
- Literature evidence available