L17* (p.Leu17Ter) variant of IAPP (Islet amyloid polypeptide)
L17* (p.Leu17Ter) in IAPP (Islet amyloid polypeptide) is a protein-truncating change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.52 / 1. The record also includes population frequency data and structural context.
L17* (p.Leu17Ter) variant details
- p.Leu17Ter
- TOPMed rs904381884
- gnomAD rs904381884
- Stop Gained
- Variant Prioritization Score for Impact Estimate 0.515
- CADD 35.00
- Most common in the African/African-American population (allele frequency 7.2e-05)
- Structural context available