L10M (p.Leu10Met) variant of IAPP (Islet amyloid polypeptide)
L10M (p.Leu10Met) in IAPP (Islet amyloid polypeptide) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.11 / 1. The record also includes population frequency data, published literature, and structural context.
L10M (p.Leu10Met) variant details
- p.Leu10Met
- gnomAD 12-21376327-T-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.113
- CADD 4.55
- Most common in the Non-Finnish European population (allele frequency 9.1e-06)
- Structural context available
- Literature evidence available