K34E (p.Lys34Glu) variant of IAPP (Islet amyloid polypeptide)
K34E (p.Lys34Glu) in IAPP (Islet amyloid polypeptide) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data, published literature, and structural context.
K34E (p.Lys34Glu) variant details
- p.Lys34Glu
- gnomAD 12-21378256-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.287
- REVEL 0.20
- CADD 25.60
- PolyPhen-2 0.74
- SIFT 0.03
- Population evidence available
- Structural context available
- Literature evidence available