I25F (p.Ile25Phe) variant of IAPP (Islet amyloid polypeptide)
I25F (p.Ile25Phe) in IAPP (Islet amyloid polypeptide) is a protein-truncating change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.12 / 1. The record also includes population frequency data, published literature, and structural context.
I25F (p.Ile25Phe) variant details
- p.Ile25Phe
- gnomAD 12-21373653-TA-T
- Frameshift
- Variant Prioritization Score for Impact Estimate 0.119
- CADD 5.44
- Population evidence available
- Structural context available
- Literature evidence available