I11T (p.Ile11Thr) variant of IAPP (Islet amyloid polypeptide)
I11T (p.Ile11Thr) in IAPP (Islet amyloid polypeptide) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.28 / 1. The record also includes population frequency data and structural context.
I11T (p.Ile11Thr) variant details
- p.Ile11Thr
- Ensembl rs925033934
- Missense
- Variant Prioritization Score for Impact Estimate 0.282
- REVEL 0.18
- CADD 14.20
- PolyPhen-2 0.00
- SIFT 0.03
- Most common in the Non-Finnish European population (allele frequency 6.3e-06)
- Structural context available