H19P (p.His19Pro) variant of IAPP (Islet amyloid polypeptide)
H19P (p.His19Pro) in IAPP (Islet amyloid polypeptide) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.25 / 1. The record also includes population frequency data and structural context.
H19P (p.His19Pro) variant details
- p.His19Pro
- TOPMed rs1279799238
- gnomAD rs1279799238
- Missense
- Variant Prioritization Score for Impact Estimate 0.249
- REVEL 0.28
- CADD 8.11
- PolyPhen-2 0.20
- SIFT 0.11
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available