G2D (p.Gly2Asp) variant of IAPP (Islet amyloid polypeptide)
G2D (p.Gly2Asp) in IAPP (Islet amyloid polypeptide) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.32 / 1. The record also includes population frequency data and structural context.
G2D (p.Gly2Asp) variant details
- p.Gly2Asp
- cosmic curated COSV53713
- Missense
- Variant Prioritization Score for Impact Estimate 0.317
- REVEL 0.26
- CADD 7.52
- PolyPhen-2 0.00
- SIFT 0.30
- Population evidence available
- Structural context available