F9S (p.Phe9Ser) variant of IAPP (Islet amyloid polypeptide)
F9S (p.Phe9Ser) in IAPP (Islet amyloid polypeptide) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.28 / 1. The record also includes population frequency data, published literature, and structural context.
F9S (p.Phe9Ser) variant details
- p.Phe9Ser
- gnomAD 12-21373377-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.275
- REVEL 0.37
- CADD 13.30
- PolyPhen-2 0.01
- SIFT 0.03
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available
- Literature evidence available