F9L (p.Phe9Leu) variant of IAPP (Islet amyloid polypeptide)
F9L (p.Phe9Leu) in IAPP (Islet amyloid polypeptide) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.16 / 1. The record also includes population frequency data and structural context.
F9L (p.Phe9Leu) variant details
- p.Phe9Leu
- cosmic curated COSV53713
- Missense
- Variant Prioritization Score for Impact Estimate 0.155
- REVEL 0.22
- CADD 0.94
- PolyPhen-2 0.00
- SIFT 0.38
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available