E31K (p.Glu31Lys) variant of IAPP (Islet amyloid polypeptide)
E31K (p.Glu31Lys) in IAPP (Islet amyloid polypeptide) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data, published literature, and structural context.
E31K (p.Glu31Lys) variant details
- p.Glu31Lys
- rs1414845423
- gnomAD 12-21373712-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.29
- CADD 6.93
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available
- Literature evidence available