E26Q (p.Glu26Gln) variant of IAPP (Islet amyloid polypeptide)
E26Q (p.Glu26Gln) in IAPP (Islet amyloid polypeptide) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.20 / 1. The record also includes population frequency data, published literature, and structural context.
E26Q (p.Glu26Gln) variant details
- p.Glu26Gln
- gnomAD 12-21373427-G-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.2
- REVEL 0.18
- CADD 13.30
- PolyPhen-2 0.54
- SIFT 0.20
- Population evidence available
- Structural context available
- Literature evidence available