C35F (p.Cys35Phe) variant of IAPP (Islet amyloid polypeptide)
C35F (p.Cys35Phe) in IAPP (Islet amyloid polypeptide) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.09 / 1. The record also includes population frequency data, published literature, and structural context.
C35F (p.Cys35Phe) variant details
- p.Cys35Phe
- gnomAD 12-21376325-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.0884
- CADD 1.10
- Most common in the African/African-American population (allele frequency 0.00019)
- Structural context available
- Literature evidence available