W55C (p.Trp55Cys) variant of HTR2C (5-hydroxytryptamine receptor 2C)
W55C (p.Trp55Cys) in HTR2C (5-hydroxytryptamine receptor 2C) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.53 / 1. The record also includes population frequency data and structural context.
W55C (p.Trp55Cys) variant details
- p.Trp55Cys
- gnomAD rs1556423325
- Missense
- Variant Prioritization Score for Impact Estimate 0.529
- REVEL 0.47
- MetaLR 0.15
- MetaSVM -0.95
- CADD 28.50
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Finnish in Finland (FIN) population (allele frequency 2.5e-05)
- Structural context available