W21C (p.Trp21Cys) variant of HTR2C (5-hydroxytryptamine receptor 2C)
W21C (p.Trp21Cys) in HTR2C (5-hydroxytryptamine receptor 2C) is a protein-truncating change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.58 / 1. The record also includes population frequency data, published literature, and structural context.
W21C (p.Trp21Cys) variant details
- p.Trp21Cys
- gnomAD X-114731319-TG-T
- Frameshift
- Variant Prioritization Score for Impact Estimate 0.581
- CADD 27.70
- Population evidence available
- Structural context available
- Literature evidence available