V8M (p.Val8Met) variant of HTR2C (5-hydroxytryptamine receptor 2C)
V8M (p.Val8Met) in HTR2C (5-hydroxytryptamine receptor 2C) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.30 / 1. The record also includes population frequency data and structural context.
V8M (p.Val8Met) variant details
- p.Val8Met
- Ensembl rs2069486549
- Missense
- Variant Prioritization Score for Impact Estimate 0.299
- REVEL 0.18
- MetaLR 0.18
- MetaSVM -0.92
- CADD 23.70
- PolyPhen-2 1.00
- SIFT 0.01
- Population evidence available
- Structural context available