V20F (p.Val20Phe) variant of HTR2C (5-hydroxytryptamine receptor 2C)
V20F (p.Val20Phe) in HTR2C (5-hydroxytryptamine receptor 2C) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data, published literature, and structural context.
V20F (p.Val20Phe) variant details
- p.Val20Phe
- gnomAD X-114731316-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.338
- REVEL 0.19
- MetaLR 0.11
- MetaSVM -0.86
- CADD 24.50
- PolyPhen-2 0.49
- SIFT 0.01
- Population evidence available
- Structural context available
- Literature evidence available