S26Y (p.Ser26Tyr) variant of HTR2C (5-hydroxytryptamine receptor 2C)
S26Y (p.Ser26Tyr) in HTR2C (5-hydroxytryptamine receptor 2C) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data and structural context.
S26Y (p.Ser26Tyr) variant details
- p.Ser26Tyr
- cosmic curated COSV52216
- Missense
- Variant Prioritization Score for Impact Estimate 0.342
- REVEL 0.12
- MetaLR 0.15
- MetaSVM -0.93
- CADD 23.30
- PolyPhen-2 0.70
- SIFT 0.00
- Population evidence available
- Structural context available