S10T (p.Ser10Thr) variant of HTR2C (5-hydroxytryptamine receptor 2C)
S10T (p.Ser10Thr) in HTR2C (5-hydroxytryptamine receptor 2C) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.26 / 1. The record also includes population frequency data, published literature, and structural context.
S10T (p.Ser10Thr) variant details
- p.Ser10Thr
- gnomAD X-114726964-T-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.257
- REVEL 0.04
- MetaLR 0.08
- MetaSVM -1.03
- CADD 13.80
- PolyPhen-2 0.00
- SIFT 0.08
- Population evidence available
- Structural context available
- Literature evidence available