S10P (p.Ser10Pro) variant of HTR2C (5-hydroxytryptamine receptor 2C)
S10P (p.Ser10Pro) in HTR2C (5-hydroxytryptamine receptor 2C) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.30 / 1. The record also includes population frequency data, published literature, and structural context.
S10P (p.Ser10Pro) variant details
- p.Ser10Pro
- gnomAD X-114726964-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.303
- REVEL 0.11
- MetaLR 0.10
- MetaSVM -1.01
- CADD 16.80
- PolyPhen-2 0.40
- SIFT 0.03
- Population evidence available
- Structural context available
- Literature evidence available