S10L (p.Ser10Leu) variant of HTR2C (5-hydroxytryptamine receptor 2C)
S10L (p.Ser10Leu) in HTR2C (5-hydroxytryptamine receptor 2C) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.26 / 1. The record also includes population frequency data and structural context.
S10L (p.Ser10Leu) variant details
- p.Ser10Leu
- gnomAD rs1556422215
- Missense
- Variant Prioritization Score for Impact Estimate 0.263
- REVEL 0.13
- MetaLR 0.08
- MetaSVM -1.02
- CADD 18.10
- PolyPhen-2 0.13
- SIFT 0.01
- Population evidence available
- Structural context available