R5M (p.Arg5Met) variant of HTR2C (5-hydroxytryptamine receptor 2C)
R5M (p.Arg5Met) in HTR2C (5-hydroxytryptamine receptor 2C) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.21 / 1. The record also includes population frequency data, published literature, and structural context.
R5M (p.Arg5Met) variant details
- p.Arg5Met
- gnomAD X-114726950-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.207
- REVEL 0.06
- MetaLR 0.08
- MetaSVM -1.04
- CADD 14.10
- PolyPhen-2 0.00
- SIFT 0.12
- Population evidence available
- Structural context available
- Literature evidence available