L4M (p.Leu4Met) variant of HTR2C (5-hydroxytryptamine receptor 2C)
L4M (p.Leu4Met) in HTR2C (5-hydroxytryptamine receptor 2C) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.17 / 1. The record also includes population frequency data, published literature, and structural context.
L4M (p.Leu4Met) variant details
- p.Leu4Met
- gnomAD X-114726946-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.172
- REVEL 0.15
- MetaLR 0.09
- MetaSVM -1.01
- CADD 15.60
- PolyPhen-2 0.01
- SIFT 0.02
- Population evidence available
- Structural context available
- Literature evidence available