L15P (p.Leu15Pro) variant of HTR2C (5-hydroxytryptamine receptor 2C)
L15P (p.Leu15Pro) in HTR2C (5-hydroxytryptamine receptor 2C) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.38 / 1. The record also includes population frequency data, published literature, and structural context.
L15P (p.Leu15Pro) variant details
- p.Leu15Pro
- gnomAD X-114731302-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.378
- REVEL 0.27
- MetaLR 0.21
- MetaSVM -0.69
- CADD 25.50
- PolyPhen-2 1.00
- SIFT 0.01
- Population evidence available
- Structural context available
- Literature evidence available