I63V (p.Ile63Val) variant of HTR2C (5-hydroxytryptamine receptor 2C)
I63V (p.Ile63Val) in HTR2C (5-hydroxytryptamine receptor 2C) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.22 / 1. The record also includes population frequency data and structural context.
I63V (p.Ile63Val) variant details
- p.Ile63Val
- ExAC rs782475474
- gnomAD rs782475474
- Missense
- Variant Prioritization Score for Impact Estimate 0.215
- REVEL 0.07
- MetaLR 0.05
- MetaSVM -1.06
- CADD 16.60
- PolyPhen-2 0.96
- SIFT 1.00
- Most common in the Non-Finnish European population (allele frequency 2.4e-06)
- Structural context available