I25F (p.Ile25Phe) variant of HTR2C (5-hydroxytryptamine receptor 2C)
I25F (p.Ile25Phe) in HTR2C (5-hydroxytryptamine receptor 2C) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.16 / 1. The record also includes population frequency data, published literature, and structural context.
I25F (p.Ile25Phe) variant details
- p.Ile25Phe
- gnomAD X-114731331-A-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.164
- REVEL 0.04
- MetaLR 0.07
- MetaSVM -1.06
- CADD 14.40
- PolyPhen-2 0.00
- SIFT 0.23
- Population evidence available
- Structural context available
- Literature evidence available